In the last few years the antidepressant activity of rubidium in the form of rubidium chloride has risen new interest. Fifteen depressed inpatients were studied for three weeks treated with Rubidium chloride. Speedy therapeutic efficacy has been shown, with lack of side effects.
Rubidium acts at the level of the central nervous system (CNS) by increasing synaptic neuro-transmitter levels. Rubidium chloride might have application in future psychochemical research and therapy of the affective disorders – particularly depressions – in an analogous way that lithium may be acting in mania.
Rubidium chloride along with other alkali minerals have long been studied for their application in treating cancer. Mass spectrographic and isotope studies have shown that potassium, rubidium, and especially cesium are most efficiently taken up by cancer cells. It is likely that rubidium and manganese, in addition to zinc, are preferentially taken up by tumors in the brain.
Alkali metals are named because they form special solutions called alkaline solutions when they are mixed with water. “Alkaline” means they have a pH greater than 7. Alkali metals include lithium, sodium, potassium, rubidium and cesium.
Dietary Sources of Rubidium:
Brazil nuts, spinach, parsley, billberry fruit, rhubarb, dandelion leaves, cashews and beets.
1. The High pH Therapy for Cancer Tests on Mice and Humans
Mass spectrographic and isotope studies have shown that potassium, rubidium, and especially cesium are most efficiently taken up by cancer cells. Tests on mice fed cesium and rubidium showed marked shrinkage in the tumor masses. The ready uptake of cesium and rubidium by the cancer cells lead the writer to the High pH therapy.
2. Rubidium Supplement Applications
Rubidium is believed to stimulate animal metabolism as a result of its chemical similarity to potassium. This resemblance enables researchers to use rubidium-87 in cardiac studies. Rubidium is used in photovoltaic cells, which convert sunlight to electricity.
3. Effect of Rubidium Chloride on the Circadian Rhythm of Locomotor Activity
The period length of the running wheel activity rhythm of cockroaches, which is lengthened by Li+ (lithium), was found to be shortened by administering rubidium chloride in the drinking water. Replacing the Rb+ (rubidium) solution by H2O for four weeks did not bring the period length back to the control value. This is probably due to the long biological half life of Rb+ in the cells. The phenomenon is another instance in which the effect of Rb+ is opposite to that of Li+.
4. Effect of Rubidium, Lithium and Cesium on Brain ATPase
Rubidium could replace potassium in the Na+K-ATPase system. K+-dependent ATPase was activated by even low rubidium concentrations.
5. Depression in Dialysis Patients: Rubidium Supplementation Before Other Drugs
It is well-known that rubidium acts at the level of the central nervous system (CNS) by increasing synaptic neurotransmitter levels, thus allowing the introduction of rubidium-based compounds as antidepressant drugs, with an efficacy as high as that of tricyclic agents, and with fewer side effects. Furthermore, many data prove that a true rubidium deficiency occurs in dialysis patients.
6. Rubidium Chloride Ingestion by Volunteer Subjects: Initial Experience
A long term study of chronic rubidium loading in one of these subjects demonstrated no undesirable clinical side effects. Rubidium chloride might have application in future psychochemical research and therapy of the affective disorders – particularly depressions – in an analogous way that lithium may be acting in mania. Rubidium increases normetanephrine formation in rat brain, an effect opposite to that seen in lithium.
7. Clinical Use of Rubidium Chloride for Depression
Thirty-one female inpatient depressives underwent a systematic open trial with rubidium chloride. By week 2, at least two-thirds had improved significantly.
8. The Pharmacological Action of Rubidium Chloride in Depression
In the last few years the antidepressant activity of Rubidium chloride has risen new interest. Fifteen depressed inpatients were studied for three weeks treated with Rubidium chloride. Speedy therapeutic efficacy has been shown, with lack of side effects.
9. Preferential Uptake of Zinc, Manganese, and Rubidium in Rat Brain Tumor
The uptake of various radionuclides was examined in rat brain tumor. It is likely that rubidium and manganese, in addition to zinc, are preferentially taken up by tumors in the brain.
10. Alkali Metals
Alkali Metals constitute group 1 of the Periodic Table (other than hydrogen). They are named Alkali Metals because when they are mixed with water they form special solutions called alkaline solutions. Alkaline means they have a pH of greater than 7 – they make basic solutions – not acids. Alkali Metals include Lithium, Sodium, Potassium, Rubidium, Cesium, and Francium. Alkali Metals have one electron in the outer shell that is easily given off. Alkali Metals become +1 charged cations (any positively charged ion is called a cation) when they give away an electron. Alkali Metals form ionic bonds with nonmetals. (They give up the outer electron.)
11. Rubidium from Staying Healthy With Nutrition
Rubidium may function like an antidepressant because of its ability to increase serotonin in rats. In studies with mice, rubidium has also helped decrease tumor growth, possibly by replacing potassium in cell transport mechanisms or by rubidium ions attaching to the cancer cell membranes.
12. Rubidium and Circadian Rhythm
Overview of rubidium’s biological roles. Rubidium competes with potassium ions for entry in to the body. Rubidium activates and mobilizes lithium. Rubidium chloride changes circadian rhythms. Rubidium partners with cobalt. Cobalt allows absorption of some 10 minerals. Rubidium enhances the release of norepinephrine. Lithium has the opposite effect. The best source of rubidium is unprocessed Brazil nuts.
13. The Minerals You Need: Rubidium
Scientists in Belgiam found that rubidium levels in the human brain fall as we age. Rubidium is needed for producing S.O.D. (superoxide dismutase), a major antioxidant.
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